V030-0153 Screening compound: 2-(2-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carboxylic acid

V030-0153 Screening compound: 2-(2-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carboxylic acid
V030-0153 Screening compound: 2-(2-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound V030-0153
2-(2-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V030-0153

Molecular Formula

C18H16ClNO3S (C18 H16 ClNO3 S)

Compound Name

2-(2-chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carboxylic acid

IUPAC name

2-(2-chlorophenyl)-3-(4-methylbenzoyl)-13-thiazolidine-4-carboxylic acid

SMILES

Cc(cc1)ccc1C(N1C(c(cccc2)c2Cl)SCC1C(O)=O)=O

InChI

InChI=1S/C18H16ClNO3S/c1-11-6-8-12(9-7-11)16(21)20-15(18(22)23)10-24-17(20)13-4-2-3-5-14(13)19/h2-9,15,17H,10H2,1H3,(H,22,23)

InChI Key

BDCKQLQRWJGVHI-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

361.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.406

Distribution Coefficient, logD

-1.127

Water Solubility, LogSw

-3.69

Polar Surface Area

44.433

Acid Dissociation Constant (pKa)

2.87

Base Dissociation Constant (pKb)

-14.62

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

22.20

V030-0153 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V030-0153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V030-0153?
Check Price and Availability of V030-0153, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V030-0153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V030-0153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V030-0153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V030-0153 available by request