V030-8754 Screening compound: N-{3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}propanamide

V030-8754 Screening compound: N-{3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}propanamide
V030-8754 Screening compound: N-{3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V030-8754
N-{3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V030-8754

Molecular Formula

C22H26N2O2S (C22 H26 N2 O2 S)

Compound Name

N-{3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}propanamide

IUPAC name

N-{3-[3-(4-tert-butylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}propanamide

SMILES

CCC(Nc1cccc(C(N2c3ccc(C(C)(C)C)cc3)SCC2=O)c1)=O

InChI

InChI=1S/C22H26N2O2S/c1-5-19(25)23-17-8-6-7-15(13-17)21-24(20(26)14-27-21)18-11-9-16(10-12-18)22(2,3)4/h6-13,21H,5,14H2,1-4H3,(H,23,25)/t21-/m0/s1

InChI Key

WIIIOTDOESAMHH-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19861476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.852

Distribution Coefficient, logD

4.852

Water Solubility, LogSw

-4.59

Polar Surface Area

39.282

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

1.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

V030-8754 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V030-8754 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V030-8754?
Check Price and Availability of V030-8754, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V030-8754 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V030-8754
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V030-8754
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V030-8754 available by request