Y010-0272 Screening compound: 5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid

Y010-0272 Screening compound: 5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid
Y010-0272 Screening compound: 5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound Y010-0272
5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y010-0272

Molecular Formula

C24H16ClNO6 (C24 H16 ClNO6)

Compound Name

5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid

IUPAC name

5-[3-benzoyl-2-(4-chlorophenyl)-4-hydroxy-5-oxo-25-dihydro-1H-pyrrol-1-yl]-2-hydroxybenzoic acid

SMILES

OC(c(cc(cc1)N(C(C(C(c2ccccc2)=O)=C2O)c(cc3)ccc3Cl)C2=O)c1O)=O

InChI

InChI=1S/C24H16ClNO6/c25-15-8-6-13(7-9-15)20-19(21(28)14-4-2-1-3-5-14)22(29)23(30)26(20)16-10-11-18(27)17(12-16)24(31)32/h1-12,20,27,29H,(H,31,32)/t20-/m1/s1

InChI Key

HOQPKLGHFSBHQC-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD00841698

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.85

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.712

Distribution Coefficient, logD

1.393

Water Solubility, LogSw

-4.74

Polar Surface Area

89.172

Acid Dissociation Constant (pKa)

4.08

Base Dissociation Constant (pKb)

-7.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.20

Y010-0272 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with Y010-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y010-0272?
Check Price and Availability of Y010-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y010-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y010-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y010-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y010-0272 available by request