Y070-4500 Screening compound: 1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-2,5-dihydro-1H-pyrrol-2-one

Y070-4500 Screening compound: 1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-2,5-dihydro-1H-pyrrol-2-one
Y070-4500 Screening compound: 1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Y070-4500
1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y070-4500

Molecular Formula

C24H17N3O4S2 (C24 H17 N3 O4 S2)

Compound Name

1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

1-[5-(benzylsulfanyl)-134-thiadiazol-2-yl]-4-(furan-2-carbonyl)-3-hydroxy-5-phenyl-25-dihydro-1H-pyrrol-2-one

SMILES

OC(C(N(C1c2ccccc2)c2nnc(SCc3ccccc3)s2)=O)=C1C(c1ccco1)=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.082

Distribution Coefficient, logD

3.804

Water Solubility, LogSw

-4.19

Polar Surface Area

75.202

Acid Dissociation Constant (pKa)

7.45

Base Dissociation Constant (pKb)

-9.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.30

Y070-4500 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with Y070-4500 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y070-4500?
Check Price and Availability of Y070-4500, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y070-4500 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y070-4500
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y070-4500
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y070-4500 available by request