Z217-0946 Screening compound: 2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide

Z217-0946 Screening compound: 2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide
Z217-0946 Screening compound: 2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z217-0946
2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z217-0946

Molecular Formula

C26H30N6O2S (C26 H30 N6 O2 S)

Compound Name

2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide

IUPAC name

2-{methyl[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[34-d][13]thiazol-5-yl]amino}-N-{[4-(morpholin-4-yl)phenyl]methyl}acetamide

SMILES

Cc(c1c2nc(N(C)CC(NCc(cc3)ccc3N3CCOCC3)=O)s1)nn2-c1ccc(C)cc1

InChI

InChI=1S/C26H30N6O2S/c1-18-4-8-22(9-5-18)32-25-24(19(2)29-32)35-26(28-25)30(3)17-23(33)27-16-20-6-10-21(11-7-20)31-12-14-34-15-13-31/h4-11H,12-17H2,1-3H3,(H,27,33)

InChI Key

GFGXWYXCAFQWDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634649

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.885

Distribution Coefficient, logD

3.885

Water Solubility, LogSw

-3.80

Polar Surface Area

63.626

Acid Dissociation Constant (pKa)

13.98

Base Dissociation Constant (pKb)

4.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

Z217-0946 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z217-0946 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z217-0946?
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What is the minimum amount of Z217-0946 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z217-0946
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z217-0946
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z217-0946 available by request