Z223-0123 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

Z223-0123 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one
Z223-0123 Screening compound: 1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-0123
1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-0123

Molecular Formula

C22H27N7O2 (C22 H27 N7 O2)

Compound Name

1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

IUPAC name

1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-[4-(pyrrolidin-1-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]ethan-1-one

SMILES

COc(cc1)ccc1N(CC1)CCN1C(Cn1ncc2c(N3CCCC3)ncnc12)=O

InChI

InChI=1S/C22H27N7O2/c1-31-18-6-4-17(5-7-18)26-10-12-27(13-11-26)20(30)15-29-22-19(14-25-29)21(23-16-24-22)28-8-2-3-9-28/h4-7,14,16H,2-3,8-13,15H2,1H3

InChI Key

ABONPSSRPMUSOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635491

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.299

Distribution Coefficient, logD

2.290

Water Solubility, LogSw

-2.39

Polar Surface Area

65.287

Acid Dissociation Constant (pKa)

19.72

Base Dissociation Constant (pKb)

5.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

Z223-0123 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Z223-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-0123?
Check Price and Availability of Z223-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-0123 available by request