Z223-2050 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethan-1-one

Z223-2050 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethan-1-one
Z223-2050 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-2050
1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-2050

Molecular Formula

C26H29N9O (C26 H29 N9 O)

Compound Name

1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethan-1-one

IUPAC name

1-(4-phenylpiperazin-1-yl)-2-{4-[4-(pyridin-2-yl)piperazin-1-yl]-1H-pyrazolo[34-d]pyrimidin-1-yl}ethan-1-one

SMILES

O=C(Cn1ncc2c(N(CC3)CCN3c3ncccc3)ncnc12)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C26H29N9O/c36-24(33-14-10-31(11-15-33)21-6-2-1-3-7-21)19-35-26-22(18-30-35)25(28-20-29-26)34-16-12-32(13-17-34)23-8-4-5-9-27-23/h1-9,18,20H,10-17,19H2

InChI Key

WTQBFSIPJKCJDT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635894

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.915

Distribution Coefficient, logD

2.905

Water Solubility, LogSw

-2.92

Polar Surface Area

69.149

Acid Dissociation Constant (pKa)

19.72

Base Dissociation Constant (pKb)

5.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

Z223-2050 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with Z223-2050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-2050?
Check Price and Availability of Z223-2050, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-2050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-2050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-2050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-2050 available by request