Z268-0788 Screening compound: N-(2-methoxyphenyl)-N'-[1,2,4]triazolo[4,3-a]pyridin-3-ylurea

Z268-0788 Screening compound: N-(2-methoxyphenyl)-N'-[1,2,4]triazolo[4,3-a]pyridin-3-ylurea
Z268-0788 Screening compound: N-(2-methoxyphenyl)-N'-[1,2,4]triazolo[4,3-a]pyridin-3-ylurea alternative view

Chemical Structure Depiction of ChemDiv screening compound Z268-0788
N-(2-methoxyphenyl)-N'-[1,2,4]triazolo[4,3-a]pyridin-3-ylurea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z268-0788

Molecular Formula

C14H13N5O2 (C14 H13 N5 O2)

Compound Name

N-(2-methoxyphenyl)-N'-[1,2,4]triazolo[4,3-a]pyridin-3-ylurea

IUPAC name

1-(2-methoxyphenyl)-3-{[124]triazolo[43-a]pyridin-3-yl}urea

SMILES

COc(cccc1)c1NC(Nc1nnc2n1cccc2)=O

InChI

InChI=1S/C14H13N5O2/c1-21-11-7-3-2-6-10(11)15-14(20)16-13-18-17-12-8-4-5-9-19(12)13/h2-9H,1H3,(H2,15,16,18,20)

InChI Key

WCRRXUOOPMRHOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637175

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

283.29

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.825

Distribution Coefficient, logD

1.825

Water Solubility, LogSw

-2.01

Polar Surface Area

62.992

Acid Dissociation Constant (pKa)

11.52

Base Dissociation Constant (pKb)

-7.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.14

Z268-0788 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z268-0788 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z268-0788?
Check Price and Availability of Z268-0788, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z268-0788 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z268-0788
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z268-0788
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z268-0788 available by request