Z269-0473 Screening compound: 4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[1,5-a]pyridine-3-carbonyl}morpholine

Z269-0473 Screening compound: 4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[1,5-a]pyridine-3-carbonyl}morpholine
Z269-0473 Screening compound: 4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[1,5-a]pyridine-3-carbonyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z269-0473
4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[1,5-a]pyridine-3-carbonyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z269-0473

Molecular Formula

C24H25BrN4O3 (C24 H25 BrN4 O3)

Compound Name

4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[1,5-a]pyridine-3-carbonyl}morpholine

IUPAC name

4-{5-[1-(2-bromobenzoyl)piperidin-4-yl]pyrazolo[15-a]pyridine-3-carbonyl}morpholine

SMILES

O=C(c1c(cc(C(CC2)CCN2C(c(cccc2)c2Br)=O)cc2)n2nc1)N1CCOCC1

InChI

InChI=1S/C24H25BrN4O3/c25-21-4-2-1-3-19(21)23(30)27-8-5-17(6-9-27)18-7-10-29-22(15-18)20(16-26-29)24(31)28-11-13-32-14-12-28/h1-4,7,10,15-17H,5-6,8-9,11-14H2

InChI Key

QEQQQSITATWDEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637421

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.450

Distribution Coefficient, logD

2.450

Water Solubility, LogSw

-2.73

Polar Surface Area

52.270

Acid Dissociation Constant (pKa)

23.93

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

Z269-0473 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z269-0473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z269-0473?
Check Price and Availability of Z269-0473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z269-0473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z269-0473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z269-0473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z269-0473 available by request