Z274-0268 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-9-(propan-2-yl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol

Z274-0268 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-9-(propan-2-yl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol
Z274-0268 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-9-(propan-2-yl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol alternative view

Chemical Structure Depiction of ChemDiv screening compound Z274-0268
2-[4-(2H-1,3-benzodioxol-5-yl)-9-(propan-2-yl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z274-0268

Molecular Formula

C24H28BrN3O3 (C24 H28 BrN3 O3)

Compound Name

2-[4-(2H-1,3-benzodioxol-5-yl)-9-(propan-2-yl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol

IUPAC name

2-[4-(2H-13-benzodioxol-5-yl)-9-(propan-2-yl)-159-triazaspiro[5.5]undec-4-en-2-yl]-4-bromophenol

SMILES

CC(C)N(CC1)CCC1(NC(C1)c(cc(cc2)Br)c2O)N=C1c(cc1)cc2c1OCO2

InChI

InChI=1S/C24H28BrN3O3/c1-15(2)28-9-7-24(8-10-28)26-19(16-3-6-22-23(11-16)31-14-30-22)13-20(27-24)18-12-17(25)4-5-21(18)29/h3-6,11-12,15,20,27,29H,7-10,13-14H2,1-2H3/t20-/m0/s1

InChI Key

XUMNOAWFUBDHSU-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD03452550

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.790

Distribution Coefficient, logD

2.067

Water Solubility, LogSw

-4.27

Polar Surface Area

58.507

Acid Dissociation Constant (pKa)

10.29

Base Dissociation Constant (pKb)

10.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.80

Z274-0268 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with Z274-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z274-0268?
Check Price and Availability of Z274-0268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z274-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z274-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z274-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z274-0268 available by request