Z301-0243 Screening compound: 2,2,2-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

Z301-0243 Screening compound: 2,2,2-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one
Z301-0243 Screening compound: 2,2,2-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z301-0243
2,2,2-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z301-0243

Molecular Formula

C18H17F4N5OS (C18 H17 F4 N5 OS)

Compound Name

2,2,2-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

IUPAC name

222-trifluoro-1-{4-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[34-d][13]thiazol-5-yl]-14-diazepan-1-yl}ethan-1-one

SMILES

Cc(c1c2nc(N(CCC3)CCN3C(C(F)(F)F)=O)s1)nn2-c(cc1)ccc1F

InChI

InChI=1S/C18H17F4N5OS/c1-11-14-15(27(24-11)13-5-3-12(19)4-6-13)23-17(29-14)26-8-2-7-25(9-10-26)16(28)18(20,21)22/h3-6H,2,7-10H2,1H3

InChI Key

GLUANBRUXYKTDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638283

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.639

Distribution Coefficient, logD

3.639

Water Solubility, LogSw

-3.81

Polar Surface Area

45.350

Acid Dissociation Constant (pKa)

23.34

Base Dissociation Constant (pKb)

0.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

Z301-0243 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Agro:
  • Agro
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z301-0243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z301-0243?
Check Price and Availability of Z301-0243, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z301-0243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z301-0243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z301-0243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z301-0243 available by request