Z318-1041 Screening compound: N-[4-(3,4-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide

Z318-1041 Screening compound: N-[4-(3,4-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide
Z318-1041 Screening compound: N-[4-(3,4-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z318-1041
N-[4-(3,4-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z318-1041

Molecular Formula

C24H35N5O5S (C24 H35 N5 O5 S)

Compound Name

N-[4-(3,4-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide

IUPAC name

N-[4-(34-diethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-1-(pyrrolidine-1-sulfonyl)piperidine-3-carboxamide

SMILES

CCOc(ccc(-c1c(NC(C(CCC2)CN2S(N2CCCC2)(=O)=O)=O)[nH]nc1C)c1)c1OCC

InChI

InChI=1S/C24H35N5O5S/c1-4-33-20-11-10-18(15-21(20)34-5-2)22-17(3)26-27-23(22)25-24(30)19-9-8-14-29(16-19)35(31,32)28-12-6-7-13-28/h10-11,15,19H,4-9,12-14,16H2,1-3H3,(H2,25,26,27,30)/t19-/m0/s1

InChI Key

ASVSFFDQGNAUJQ-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27644008

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.64

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.532

Distribution Coefficient, logD

1.532

Water Solubility, LogSw

-2.54

Polar Surface Area

95.873

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

0.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

58.30

Z318-1041 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Immunological Library (6760 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Proteases
  • Proteases
  • Others

References: we are preparing a list of scientific research reports with Z318-1041 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z318-1041?
Check Price and Availability of Z318-1041, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z318-1041 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z318-1041
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z318-1041
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z318-1041 available by request