Z341-0195 Screening compound: N-(2-fluorobenzyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

Z341-0195 Screening compound: N-(2-fluorobenzyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide
Z341-0195 Screening compound: N-(2-fluorobenzyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z341-0195
N-(2-fluorobenzyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z341-0195

Molecular Formula

C25H28FN5O2S (C25 H28 FN5 O2 S)

Compound Name

N-(2-fluorobenzyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

IUPAC name

N-[(2-fluorophenyl)methyl]-1-[3-methyl-5-(pyrrolidine-1-carbonyl)-[12]thiazolo[54-b]pyridin-4-yl]piperidine-4-carboxamide

SMILES

Cc1nsc2ncc(C(N3CCCC3)=O)c(N(CC3)CCC3C(NCc(cccc3)c3F)=O)c12

InChI

InChI=1S/C25H28FN5O2S/c1-16-21-22(19(15-28-24(21)34-29-16)25(33)31-10-4-5-11-31)30-12-8-17(9-13-30)23(32)27-14-18-6-2-3-7-20(18)26/h2-3,6-7,15,17H,4-5,8-14H2,1H3,(H,27,32)

InChI Key

MFXVATTZUQNUDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638551

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.102

Distribution Coefficient, logD

3.101

Water Solubility, LogSw

-3.47

Polar Surface Area

64.809

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

Z341-0195 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Others

References: we are preparing a list of scientific research reports with Z341-0195 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z341-0195?
Check Price and Availability of Z341-0195, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z341-0195 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z341-0195
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z341-0195
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z341-0195 available by request