Z341-0450 Screening compound: ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-amido}benzoate

Z341-0450 Screening compound: ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-amido}benzoate
Z341-0450 Screening compound: ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound Z341-0450
ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z341-0450

Molecular Formula

C29H35N5O4S (C29 H35 N5 O4 S)

Compound Name

ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-amido}benzoate

IUPAC name

ethyl 4-{1-[3-methyl-5-(4-methylpiperidine-1-carbonyl)-[12]thiazolo[54-b]pyridin-4-yl]piperidine-4-amido}benzoate

SMILES

CCOC(c(cc1)ccc1NC(C(CC1)CCN1c1c(c(C)ns2)c2ncc1C(N1CCC(C)CC1)=O)=O)=O

InChI

InChI=1S/C29H35N5O4S/c1-4-38-29(37)21-5-7-22(8-6-21)31-26(35)20-11-15-33(16-12-20)25-23(17-30-27-24(25)19(3)32-39-27)28(36)34-13-9-18(2)10-14-34/h5-8,17-18,20H,4,9-16H2,1-3H3,(H,31,35)

InChI Key

ZEPCXQZINHZJGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638610

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

549.69

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.257

Distribution Coefficient, logD

4.256

Water Solubility, LogSw

-4.21

Polar Surface Area

83.874

Acid Dissociation Constant (pKa)

10.39

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.30

Z341-0450 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z341-0450 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z341-0450?
Check Price and Availability of Z341-0450, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z341-0450 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z341-0450
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z341-0450
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z341-0450 available by request