Z347-0145 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

Z347-0145 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine
Z347-0145 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z347-0145
N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z347-0145

Molecular Formula

C22H26N4O3S (C22 H26 N4 O3 S)

Compound Name

N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

IUPAC name

N-[2-(34-dimethoxyphenyl)ethyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[34-d]pyrimidin-4-amine

SMILES

Cc1c2c(NCCc(cc3)cc(OC)c3OC)ncnc2c(C(N2CCCC2)=O)s1

InChI

InChI=1S/C22H26N4O3S/c1-14-18-19(20(30-14)22(27)26-10-4-5-11-26)24-13-25-21(18)23-9-8-15-6-7-16(28-2)17(12-15)29-3/h6-7,12-13H,4-5,8-11H2,1-3H3,(H,23,24,25)

InChI Key

KICMUSJPBCJJDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638717

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.338

Distribution Coefficient, logD

3.335

Water Solubility, LogSw

-3.88

Polar Surface Area

64.543

Acid Dissociation Constant (pKa)

16.44

Base Dissociation Constant (pKb)

5.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

Z347-0145 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with Z347-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z347-0145?
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What is the minimum amount of Z347-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z347-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z347-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z347-0145 available by request