Z347-0165 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

Z347-0165 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine
Z347-0165 Screening compound: N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z347-0165
N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z347-0165

Molecular Formula

C19H18ClFN4OS (C19 H18 ClFN4 OS)

Compound Name

N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-amine

IUPAC name

N-[(3-chloro-4-fluorophenyl)methyl]-5-methyl-7-(pyrrolidine-1-carbonyl)thieno[34-d]pyrimidin-4-amine

SMILES

Cc1c2c(NCc(cc3)cc(Cl)c3F)ncnc2c(C(N2CCCC2)=O)s1

InChI

InChI=1S/C19H18ClFN4OS/c1-11-15-16(17(27-11)19(26)25-6-2-3-7-25)23-10-24-18(15)22-9-12-4-5-14(21)13(20)8-12/h4-5,8,10H,2-3,6-7,9H2,1H3,(H,22,23,24)

InChI Key

QQTCCOAYTNFUMN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638722

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.079

Distribution Coefficient, logD

4.076

Water Solubility, LogSw

-4.46

Polar Surface Area

49.441

Acid Dissociation Constant (pKa)

14.65

Base Dissociation Constant (pKb)

5.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

Z347-0165 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with Z347-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z347-0165?
Check Price and Availability of Z347-0165, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z347-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z347-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z347-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z347-0165 available by request