Z354-0972 Screening compound: 1-(1-{2-CYCLOBUTYL-5-METHYLTHIENO[3,4-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBONYL)-4-(PYRIDIN-2-YL)PIPERAZINE

Z354-0972 Screening compound: 1-(1-{2-CYCLOBUTYL-5-METHYLTHIENO[3,4-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBONYL)-4-(PYRIDIN-2-YL)PIPERAZINE
Z354-0972 Screening compound: 1-(1-{2-CYCLOBUTYL-5-METHYLTHIENO[3,4-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBONYL)-4-(PYRIDIN-2-YL)PIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound Z354-0972
1-(1-{2-CYCLOBUTYL-5-METHYLTHIENO[3,4-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBONYL)-4-(PYRIDIN-2-YL)PIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z354-0972

Molecular Formula

C26H32N6OS (C26 H32 N6 OS)

Compound Name

1-(1-{2-CYCLOBUTYL-5-METHYLTHIENO[3,4-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBONYL)-4-(PYRIDIN-2-YL)PIPERAZINE

IUPAC name

n/a

SMILES

Cc1c2c(N(CC3)CCC3C(N(CC3)CCN3c3ncccc3)=O)nc(C3CCC3)nc2cs1

InChI

InChI=1S/C26H32N6OS/c1-18-23-21(17-34-18)28-24(19-5-4-6-19)29-25(23)31-11-8-20(9-12-31)26(33)32-15-13-30(14-16-32)22-7-2-3-10-27-22/h2-3,7,10,17,19-20H,4-6,8-9,11-16H2,1H3

InChI Key

QPPMUBSABAMCQO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.65

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.587

Distribution Coefficient, logD

2.211

Water Solubility, LogSw

-4.52

Polar Surface Area

51.600

Acid Dissociation Constant (pKa)

20.75

Base Dissociation Constant (pKb)

9.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.80

Z354-0972 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z354-0972 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z354-0972?
Check Price and Availability of Z354-0972, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z354-0972 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z354-0972
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z354-0972
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z354-0972 available by request