Z354-1046 Screening compound: 1-(2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl)-N~4~-cyclohexyl-4-piperidinecarboxamide

Z354-1046 Screening compound: 1-(2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl)-N~4~-cyclohexyl-4-piperidinecarboxamide
Z354-1046 Screening compound: 1-(2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl)-N~4~-cyclohexyl-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z354-1046
1-(2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl)-N~4~-cyclohexyl-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z354-1046

Molecular Formula

C23H32N4OS (C23 H32 N4 OS)

Compound Name

1-(2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl)-N~4~-cyclohexyl-4-piperidinecarboxamide

IUPAC name

n/a

SMILES

Cc1c2c(N(CC3)CCC3C(NC3CCCCC3)=O)nc(C3CCC3)nc2cs1

InChI

InChI=1S/C23H32N4OS/c1-15-20-19(14-29-15)25-21(16-6-5-7-16)26-22(20)27-12-10-17(11-13-27)23(28)24-18-8-3-2-4-9-18/h14,16-18H,2-13H2,1H3,(H,24,28)

InChI Key

HZQNKKJGHXORPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638836

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.822

Distribution Coefficient, logD

2.446

Water Solubility, LogSw

-4.62

Polar Surface Area

47.319

Acid Dissociation Constant (pKa)

15.04

Base Dissociation Constant (pKb)

9.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

69.60

Z354-1046 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with Z354-1046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z354-1046?
Check Price and Availability of Z354-1046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z354-1046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z354-1046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z354-1046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z354-1046 available by request