Z603-1397 Screening compound: 1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-1,4-diazepane

Z603-1397 Screening compound: 1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-1,4-diazepane
Z603-1397 Screening compound: 1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-1,4-diazepane alternative view

Chemical Structure Depiction of ChemDiv screening compound Z603-1397
1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-1,4-diazepane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z603-1397

Molecular Formula

C16H23N3O (C16 H23 N3 O)

Compound Name

1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-1,4-diazepane

IUPAC name

1-cyclobutanecarbonyl-4-[(pyridin-2-yl)methyl]-14-diazepane

SMILES

O=C(C1CCC1)N1CCN(Cc2ncccc2)CCC1

InChI

InChI=1S/C16H23N3O/c20-16(14-5-3-6-14)19-10-4-9-18(11-12-19)13-15-7-1-2-8-17-15/h1-2,7-8,14H,3-6,9-13H2

InChI Key

BQWVEUSPWPSKGF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27639980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

273.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

0.875

Distribution Coefficient, logD

0.687

Water Solubility, LogSw

-1.37

Polar Surface Area

30.824

Acid Dissociation Constant (pKa)

23.62

Base Dissociation Constant (pKb)

7.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

62.50

Z603-1397 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Structure:
  • Fragments
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z603-1397 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z603-1397?
Check Price and Availability of Z603-1397, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z603-1397 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z603-1397
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z603-1397
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z603-1397 available by request