Z606-1196 Screening compound: 1-[3-(4-isopropyl-1,3-thiazol-2-yl)piperidino]-2,2-dimethyl-1-propanone

Z606-1196 Screening compound: 1-[3-(4-isopropyl-1,3-thiazol-2-yl)piperidino]-2,2-dimethyl-1-propanone
Z606-1196 Screening compound: 1-[3-(4-isopropyl-1,3-thiazol-2-yl)piperidino]-2,2-dimethyl-1-propanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z606-1196
1-[3-(4-isopropyl-1,3-thiazol-2-yl)piperidino]-2,2-dimethyl-1-propanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z606-1196

Molecular Formula

C16H26N2OS (C16 H26 N2 OS)

Compound Name

1-[3-(4-isopropyl-1,3-thiazol-2-yl)piperidino]-2,2-dimethyl-1-propanone

IUPAC name

22-dimethyl-1-{3-[4-(propan-2-yl)-13-thiazol-2-yl]piperidin-1-yl}propan-1-one

SMILES

CC(C)c1csc(C(CCC2)CN2C(C(C)(C)C)=O)n1

InChI

InChI=1S/C16H26N2OS/c1-11(2)13-10-20-14(17-13)12-7-6-8-18(9-12)15(19)16(3,4)5/h10-12H,6-9H2,1-5H3/t12-/m0/s1

InChI Key

QSAMYNNJZPXKSH-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27640523

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

3.741

Distribution Coefficient, logD

3.739

Water Solubility, LogSw

-3.76

Polar Surface Area

26.826

Acid Dissociation Constant (pKa)

26.84

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

75.00

Z606-1196 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z606-1196 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z606-1196?
Check Price and Availability of Z606-1196, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z606-1196 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z606-1196
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z606-1196
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z606-1196 available by request