ZE09-0745 Screening compound: 2-chloro-1-[4-(6-phenyl-4-pyrimidinyl)piperazino]-1-propanone

ZE09-0745 Screening compound: 2-chloro-1-[4-(6-phenyl-4-pyrimidinyl)piperazino]-1-propanone
ZE09-0745 Screening compound: 2-chloro-1-[4-(6-phenyl-4-pyrimidinyl)piperazino]-1-propanone alternative view

Chemical Structure Depiction of ChemDiv screening compound ZE09-0745
2-chloro-1-[4-(6-phenyl-4-pyrimidinyl)piperazino]-1-propanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

ZE09-0745

Molecular Formula

C17H19ClN4O (C17 H19 ClN4 O)

Compound Name

2-chloro-1-[4-(6-phenyl-4-pyrimidinyl)piperazino]-1-propanone

IUPAC name

2-chloro-1-[4-(6-phenylpyrimidin-4-yl)piperazin-1-yl]propan-1-one

SMILES

CC(C(N(CC1)CCN1c1ncnc(-c2ccccc2)c1)=O)Cl

InChI

InChI=1S/C17H19ClN4O/c1-13(18)17(23)22-9-7-21(8-10-22)16-11-15(19-12-20-16)14-5-3-2-4-6-14/h2-6,11-13H,7-10H2,1H3/t13-/m0/s1

InChI Key

PLJSIVQYYYACSI-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD32262830

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.450

Distribution Coefficient, logD

3.447

Water Solubility, LogSw

-3.68

Polar Surface Area

39.420

Acid Dissociation Constant (pKa)

19.60

Base Dissociation Constant (pKb)

5.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.29

ZE09-0745 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

Covalent Fragments Smart Library (839 compounds)

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with ZE09-0745 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound ZE09-0745?
Check Price and Availability of ZE09-0745, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of ZE09-0745 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for ZE09-0745
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for ZE09-0745
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of ZE09-0745 available by request