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Pharma News
Pharma News
IU Researchers Identify Clotting Protein as Target in Pancreatic Cancer
Indiana University researchers found that depleting fibrinogen, a liver clotting protein, slows pancreatic cancer growth and reduces liver metastasis.
Hoth Therapeutics Data: HT-VA Restores Cholesterol in Female MASLD Model
Hoth Therapeutics announces positive female preclinical data showing HT-VA (GDNF) restores cholesterol and improves lipid metabolism in a MASLD model.
FDA Widens Approval of Leucovorin, a Drug Previously Hyped for Autism
FDA expands approval for leucovorin to treat cerebral folate deficiency with FOLR1 variant, clarifying its use after prior hype as a broad autism treatment.
EMA Proposes Faster Clinical Trial Approvals During Health Emergencies
EMA proposes new draft guidelines to accelerate clinical trial approvals during public health emergencies, prioritizing robust data and participant safety.
Servier Buys Day One Biopharmaceuticals for $2.5bn in Rare Cancer Deal
Servier acquires Day One Biopharmaceuticals for $2.5bn, adding Ojemda (tovorafenib) for pediatric glioma to its growing rare oncology pipeline.
Amplia Data: Narmafotinib Enhances kRAS Inhibitors in Mutated Cancers
Amplia Therapeutics presented preclinical data showing its FAK inhibitor narmafotinib enhances kRAS inhibitors in mutated pancreatic and lung cancers.
Vinay Prasad Leaves FDA Again Amidst Leadership Shake-ups & Controversies
Vinay Prasad leaves his role as FDA's CBER head after eight months. His departure marks another major leadership change amid ongoing agency controversies.
AI Tool Streamlines Drug Synthesis, Cutting Lab Work From Months to Days
A new machine-learning system trained on sparse data predicts molecular formation, cutting months of drug synthesis lab work to days at a fraction of cost.
Study Links Gestational Diabetes & Prenatal Depression to Child Obesity
A new study explores the combined effects of gestational diabetes and prenatal depression, revealing a 43% higher risk of childhood obesity in offspring.
Affinia’s AFTX-201 Gene Therapy Earns FDA Fast Track for BAG3 Heart Disease
Affinia Therapeutics receives FDA Fast Track designation for AFTX-201, an engineered gene therapy for BAG3-associated dilated cardiomyopathy (DCM) treatment.
J&J Secures FDA Approval for Tecvayli-Darzalex Multiple Myeloma Combo
Johnson & Johnson secures FDA approval for the Tecvayli and Darzalex Faspro combination to treat adults with relapsed or refractory multiple myeloma.
Phase 2a Trial Data Shows Alnodesertib Slows Ovarian Cancer Progression
Phase 2a trial data reveals that adding low-dose alnodesertib to chemotherapy may slow disease progression in platinum-resistant ovarian cancer patients.
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