Bosutinib
Chemical Structure Depiction of
Bosutinib
Bosutinib
Compound characteristics
| Compound ID: | CE01-0186 |
| Compound Name: | Bosutinib |
| Molecular Weight: | 530.45 |
| Molecular Formula: | C26 H29 Cl2 N5 O3 |
| CAS Number: | 380843-75-4 |
| Smiles: | CN1CCN(CCCOc2cc3c(cc2OC)c(c(C#N)cn3)Nc2cc(c(cc2[Cl])[Cl])OC)CC1 |
| InChI Key: | UBPYILGKFZZVDX-UHFFFAOYSA-N |
| Short Description: | Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases. |
| Pathway: | Tyrosine Kinase/Adaptors|||Angiogenesis|||Autophagy|||Cytoskeletal Signaling |
| Target: | Autophagy|||Bcr-Abl|||Src |
| Type of molecule: | FDA Approved/Clinical |
| Alias: | SKI-606 |
| Stock amount: | 4368 |