BAY-985
Chemical Structure Depiction of
BAY-985
BAY-985
Compound characteristics
| Compound ID: | CE01-1560 |
| Compound Name: | BAY-985 |
| Molecular Weight: | 553.59 |
| Molecular Formula: | C27 H30 F3 N9 O |
| CAS Number: | 2409479-29-2 |
| Smiles: | C[C@H](c1ccnc(c1)Nc1nc2ccc(cc2[nH]1)c1cc(ncn1)N(C)C)N1CCN(CC1)C(CC(F)(F)F)=O |
| InChI Key: | HZRJHVDNTDBTOZ-QGZVFWFLSA-N |
| Short Description: | BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKepsilon (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKepsilon) with antitumor efficacy. |
| Pathway: | NF-Kappab |
| Target: | IkappaB/IKK |
| Stock amount: | 401 |