Epertinib
Chemical Structure Depiction of
Epertinib
Epertinib
Compound characteristics
| Compound ID: | CE01-2403 |
| Compound Name: | Epertinib |
| Molecular Weight: | 560.03 |
| Molecular Formula: | C30 H27 Cl F N5 O3 |
| CAS Number: | 908305-13-5 |
| Smiles: | CC#CC(\c1ccc2c(c1)c(Nc1ccc(c(c1)[Cl])OCc1cccc(c1)F)ncn2)=N/OC[C@H]1COCCN1 |
| InChI Key: | IBCIAMOTBDGBJN-XMMPIXPASA-N |
| Short Description: | Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity. |
| Pathway: | Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling |
| Target: | HER|||EGFR |
| Alias: | S-22611 |
| Stock amount: | 100 |