Equisetin
Chemical Structure Depiction of
Equisetin
Equisetin
Compound characteristics
| Compound ID: | CE01-2409 |
| Compound Name: | Equisetin |
| Molecular Weight: | 373.49 |
| Molecular Formula: | C22 H31 N O4 |
| CAS Number: | 57749-43-6 |
| Smiles: | [H][C@]12C[C@H](C)CC[C@@]2([H])[C@](C)(/C(=C2/C([C@H](CO)N(C)C2=O)=O)O)[C@H](/C=C/C)C=C1 |
| InChI Key: | QNQBPPQLRODXET-BOHFPZBOSA-N |
| Short Description: | Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS- regulated virulence phenotypes in P. aeruginosa, presenting a potent lead for treating P. aeruginosa infections without hindering bacterial growth. This tetramate-containing natural product possesses antibiotic and cytotoxic properties, effectively inhibiting the growth of Gram-positive bacteria and HIV-1 integrase activity, yet it does not impact Gram-negative bacteria. |
| Pathway: | Others |
| Target: | Others |
| Stock amount: | 100 |