GGTI-2418
Chemical Structure Depiction of
GGTI-2418
GGTI-2418
Compound characteristics
| Compound ID: | CE01-2611 |
| Compound Name: | GGTI-2418 |
| Molecular Weight: | 441.53 |
| Molecular Formula: | C23 H31 N5 O4 |
| CAS Number: | 501010-06-6 |
| Smiles: | CC(C)C[C@@H](C(O)=O)NC(N1CCN(Cc2c(C)nc[nH]2)C([C@@H]1Cc1ccccc1)=O)=O |
| InChI Key: | COLCNDRDBCLVOC-ICSRJNTNSA-N |
| Short Description: | GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), showing inhibitory activities with IC50 values of 9.5 nM for GGTase I and 53 muM for FTase , respectively. Additionally, it enhances p27(Kip1) expression and induces significant regression of breast tumors. |
| Pathway: | Metabolism |
| Target: | Transferase |
| Stock amount: | 2 |