Ribociclib succinate
Chemical Structure Depiction of
Ribociclib succinate
Ribociclib succinate
Compound characteristics
| Compound ID: | CE01-9800 |
| Compound Name: | Ribociclib succinate |
| Molecular Weight: | 552.63 |
| Molecular Formula: | C23 H30 N8 O.C4 H6 O4 |
| CAS Number: | 1374639-75-4 |
| Smiles: | CN(C)C(c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1)=O.C(CC(O)=O)C(O)=O |
| InChI Key: | NHANOMFABJQAAH-UHFFFAOYSA-N |
| Short Description: | Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
| Pathway: | Cell Cycle/Checkpoint |
| Target: | CDK |
| Type of molecule: | FDA Approved/Clinical |
| Alias: | LEE011 succinate |
| Stock amount: | 3450 |