SAFit2
Chemical Structure Depiction of
SAFit2
SAFit2
Compound characteristics
| Compound ID: | CE02-0947 |
| Compound Name: | SAFit2 |
| Molecular Weight: | 803.01 |
| Molecular Formula: | C46 H62 N2 O10 |
| CAS Number: | 1643125-33-0 |
| Smiles: | COc1ccc(CC[C@H](c2cccc(c2)OCCN2CCOCC2)OC([C@@H]2CCCCN2C([C@@H](C2CCCCC2)c2cc(c(c(c2)OC)OC)OC)=O)=O)cc1OC |
| InChI Key: | ZDBWLRLGUBSLPG-FDHYQTMZSA-N |
| Short Description: | SAFit2 is a highly effective and selective fk506 binding protein 51(FKBP51) inhibitor (Ki: 6 nM). SAFit2 can enhance AKT2-AS160 binding and participate in the downstream response of glucocorticoid rel ease in vivo, and is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety. |
| Pathway: | Apoptosis|||Immunology/Inflammation|||Autophagy |
| Target: | FKBP |
| Stock amount: | 213 |