WR99210
Chemical Structure Depiction of
WR99210
WR99210
Compound characteristics
| Compound ID: | CE02-1386 |
| Compound Name: | WR99210 |
| Molecular Weight: | 394.69 |
| Molecular Formula: | C14 H18 Cl3 N5 O2 |
| CAS Number: | 47326-86-3 |
| Smiles: | CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(c(cc1[Cl])[Cl])[Cl] |
| InChI Key: | MJZJYWCQPMNPRM-UHFFFAOYSA-N |
| Short Description: | WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P. vivax and P. falciparum strains (inclu ding P. falciparum strains resistant to Pyrimethamine ) and T. gondii. |
| Pathway: | Metabolism|||Microbiology/Virology|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair |
| Target: | Antibacterial|||Antifolate|||DHFR |
| Stock amount: | 100 |