PD153035 hydrochloride
Chemical Structure Depiction of
PD153035 hydrochloride
PD153035 hydrochloride
Compound characteristics
| Compound ID: | CE02-1731 |
| Compound Name: | PD153035 hydrochloride |
| Molecular Weight: | 396.67 |
| Molecular Formula: | C16 H14 Br N3 O2.H Cl |
| CAS Number: | 183322-45-4 |
| Smiles: | COc1cc2c(Nc3cccc(c3)[Br])ncnc2cc1OC.[Cl] |
| InChI Key: | ZJOKWAWPAPMNIM-UHFFFAOYSA-N |
| Short Description: | PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src. |
| Pathway: | JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis |
| Target: | EGFR |
| Type of molecule: | Preclinical |
| Alias: | SU 5271 , Tyrphostin AG 1517 , AG 1517 , ZM 252868 HCl , PD153035 HCl , ZM 252868 |
| Stock amount: | 2381 |