Afuresertib
Chemical Structure Depiction of
Afuresertib
Afuresertib
Compound characteristics
| Compound ID: | CE02-3234 |
| Compound Name: | Afuresertib |
| Molecular Weight: | 427.33 |
| Molecular Formula: | C18 H17 Cl2 F N4 O S |
| CAS Number: | 1047644-62-1 |
| Smiles: | Cn1c(c2cc(C(N[C@@H](Cc3cccc(c3)F)CN)=O)sc2[Cl])c(cn1)[Cl] |
| InChI Key: | AFJRDFWMXUECEW-LBPRGKRZSA-N |
| Short Description: | Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. |
| Pathway: | PI3K/Akt/mTOR signaling|||Stem Cells|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling |
| Target: | ROCK|||Akt|||PKC |
| Type of molecule: | Clinical |
| Alias: | GSK2110183C , GSK2110183 |
| Stock amount: | 1833 |