TH588
Chemical Structure Depiction of
TH588
TH588
Compound characteristics
| Compound ID: | CE02-4421 |
| Compound Name: | TH588 |
| Molecular Weight: | 295.17 |
| Molecular Formula: | C13 H12 Cl2 N4 |
| CAS Number: | 1609960-31-7 |
| Smiles: | C1CC1Nc1cc(c2cccc(c2[Cl])[Cl])nc(N)n1 |
| InChI Key: | PNMYJIOQIAEYQL-UHFFFAOYSA-N |
| Short Description: | TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells. |
| Pathway: | DNA Damage/DNA Repair|||Cell Cycle/Checkpoint |
| Target: | MTH1|||DNA/RNA Synthesis |
| Stock amount: | 706 |