DM1-SMe
Chemical Structure Depiction of
DM1-SMe
DM1-SMe
Compound characteristics
| Compound ID: | CE02-5428 |
| Compound Name: | DM1-SMe |
| Molecular Weight: | 784.39 |
| Molecular Formula: | C36 H50 Cl N3 O10 S2 |
| CAS Number: | 138148-68-2 |
| Smiles: | [H][C@]12C[C@]([C@@H](\C=C/C=C(/C)Cc3cc(c(c(c3)OC)[Cl])N(C)C(C[C@@H]([C@@]3(C)[C@]([H])([C@@H]1C)O3)OC([C@H](C)N(C)C(CCSSC)=O)=O)=O)OC)(NC(=O)O2)O |
| InChI Key: | ZLUUPZXOPGORNG-ZXWAKXAPSA-N |
| Short Description: | DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines. |
| Pathway: | Cytoskeletal Signaling |
| Target: | Microtubule Associated |
| Alias: | DM1-SSMe |
| Stock amount: | 940 |