3MB-PP1
Chemical Structure Depiction of
3MB-PP1
3MB-PP1
Compound characteristics
| Compound ID: | CE02-5633 |
| Compound Name: | 3MB-PP1 |
| Molecular Weight: | 295.39 |
| Molecular Formula: | C17 H21 N5 |
| CAS Number: | 956025-83-5 |
| Smiles: | Cc1cccc(Cc2c3c(N)ncnc3n(C(C)(C)C)n2)c1 |
| InChI Key: | FYCOTGCSHZKHPR-UHFFFAOYSA-N |
| Short Description: | 3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting P lk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 muM. 3MB-PP1 can be used for the research of cell divisi on and hypha formation of Candida albicans. |
| Pathway: | Cell Cycle/Checkpoint |
| Target: | PLK |
| Stock amount: | 3979 |