Calpain Inhibitor XII

Chemical Structure Depiction of
Calpain Inhibitor XII
Pack Size, mg
$1170
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Compound characteristics

Compound ID: CE02-5802
Compound Name: Calpain Inhibitor XII
Molecular Weight: 482.58
Molecular Formula: C26 H34 N4 O5
CAS Number: 181769-57-3
Smiles: CCCC(C(C(NCc1ccccn1)=O)=O)NC(C(CC(C)C)NC(=O)OCc1ccccc1)=O
InChI Key: PLVWMBFPIAQRHK-UHFFFAOYSA-N
Short Description: (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (mu-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and ca thepsin B (Ki=750 nM). This compound is potentially useful for investigating calpains' involvement in various processes such as neutrophil chemotaxis, neuronal signaling, and cardiac responses to inju ry [1].
Stock amount: 25
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