Dasatinib hydrochloride

Chemical Structure Depiction of
Dasatinib hydrochloride
Pack Size, mg
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Compound characteristics

Compound ID: CE02-6015
Compound Name: Dasatinib hydrochloride
Molecular Weight: 524.47
Molecular Formula: C22 H26 Cl N7 O2 S.H Cl
CAS Number: 854001-07-3
Smiles: Cc1cccc(c1NC(c1cnc(Nc2cc(nc(C)n2)N2CCN(CC2)CCO)s1)=O)[Cl].[Cl]
InChI Key: MSCGWICDJYLQOJ-UHFFFAOYSA-N
Short Description: Dasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induc es Apoptosis and Autophagy.
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling
Target: c-Kit|||Bcr-Abl|||Src
Type of molecule: FDA Approved/Clinical
Alias: BMS-354825 HCl
Stock amount: 966
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