Taletrectinib
Chemical Structure Depiction of
Taletrectinib
Taletrectinib
Compound characteristics
| Compound ID: | CE02-6029 |
| Compound Name: | Taletrectinib |
| Molecular Weight: | 551.62 |
| Molecular Formula: | C23 H24 F N5 O.C6 H10 O4 |
| CAS Number: | 1505515-69-4 |
| Smiles: | C[C@H](COc1ccc(cc1)c1cnc2ccc(N[C@H](C)c3cccc(c3)F)nn12)N.C(CCC(O)=O)CC(O)=O |
| InChI Key: | DORJQZDOULKINH-QNBGGDODSA-N |
| Short Description: | Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively. |
| Pathway: | Tyrosine Kinase/Adaptors|||Immunology/Inflammation |
| Target: | ROS|||ROS Kinase|||Trk receptor |
| Type of molecule: | Clinical |
| Alias: | DS-6051b , AB-106 |
| Stock amount: | 614 |