AT9283
Chemical Structure Depiction of
AT9283
AT9283
Compound characteristics
| Compound ID: | CE03-4973 |
| Compound Name: | AT9283 |
| Molecular Weight: | 381.44 |
| Molecular Formula: | C19 H23 N7 O2 |
| CAS Number: | 896466-04-9 |
| Smiles: | C1CC1NC(Nc1c[nH]nc1c1nc2cc(CN3CCOCC3)ccc2[nH]1)=O |
| InChI Key: | LOLPPWBBNUVNQZ-UHFFFAOYSA-N |
| Short Description: | AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I). |
| Pathway: | Cell Cycle/Checkpoint|||Autophagy|||JAK/STAT signaling|||Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Chromatin/Epigenetic|||Stem Cells|||Cytoskeletal Signaling |
| Target: | Bcr-Abl|||Apoptosis|||Autophagy|||Aurora Kinase|||FLT|||JAK |
| Type of molecule: | Clinical |
| Alias: | J-504568 |
| Stock amount: | 804 |