Napyradiomycin A1

Chemical Structure Depiction of
Napyradiomycin A1
Pack Size, mg
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Compound characteristics

Compound ID: CE04-0020
Compound Name: Napyradiomycin A1
Molecular Weight: 481.42
Molecular Formula: C25 H30 Cl2 O5
CAS Number: 103106-24-7
Smiles: CC(C)=CCCC(\C)=C\C[C@]12C(c3cc(cc(c3C([C@]1(C[C@H](C(C)(C)O2)[Cl])[Cl])=O)O)O)=O
InChI Key: BCPWMPCOEAOEDD-LQGLAIQGSA-N
Short Description: Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1 .56-12.5 mug/ml).1Napyradiomycin A1is an estrogen receptor antagonist (IC50= 4.2 muM in rat uterine homogenates).2It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinat e:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 muM, respectively).3
Alias: Napyradiomycin A1
Stock amount: 1
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