SB-612111
Chemical Structure Depiction of
SB-612111
SB-612111
Compound characteristics
| Compound ID: | CE04-0671 |
| Compound Name: | SB-612111 |
| Molecular Weight: | 418.41 |
| Molecular Formula: | C24 H29 Cl2 N O |
| CAS Number: | 371980-98-2 |
| Smiles: | Cc1cccc2c1CC[C@@H](C[C@@H]2O)CN1CCC(CC1)c1c(cccc1[Cl])[Cl] |
| InChI Key: | OHRDCQFCAWLDBP-SBUREZEXSA-N |
| Short Description: | SB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for mu-, kappa- and delta-rec eptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model[1]. |
| Stock amount: | 100 |