Ternatin

Chemical Structure Depiction of
Ternatin
Pack Size, mg
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Compound characteristics

Compound ID: CE04-0754
Compound Name: Ternatin
Molecular Weight: 737.98
Molecular Formula: C37 H67 N7 O8
CAS Number: 148619-41-4
Smiles: [H][C@]1(C(N(C)[C@@H](C)C(N(C)[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N(C)[C@@H](C)C(N(C)[C@H](C)C(N[C@@]([H])(C(N1)=O)[C@@H](C(C)C)O)=O)=O)=O)=O)=O)=O)[C@@H](C)CC
InChI Key: ZMFVAIFXJWEOMH-PPDIWPMVSA-N
Short Description: Ternatin is a cyclic heptapeptide first isolated from the mushroom C. versicolor that has been shown to have cytotoxic and anti-adipogenic effects in vitro. It inhibits adipogenesis with an IC50 value of 27 nM and becomes cytotoxic to 3T3-L1 mouse adipocytes at 10-fold higher concentrations. Ternatin is reported to inhibit HCT116 cell proliferation with an IC50 value of 71 nM. Note that this metab olite should not be confused with the plant flavonoid of the same name.
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