C18 Phytoceramide (t18:0/18:0)
Chemical Structure Depiction of
C18 Phytoceramide (t18:0/18:0)
C18 Phytoceramide (t18:0/18:0)
Compound characteristics
| Compound ID: | CE04-1625 |
| Compound Name: | C18 Phytoceramide (t18:0/18:0) |
| Molecular Weight: | 583.98 |
| Molecular Formula: | C36 H73 N O4 |
| CAS Number: | 34354-88-6 |
| Smiles: | CCCCCCCCCCCCCCCCCC(N[C@@H](CO)[C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)=O |
| InChI Key: | IEZRNEGTKRQRFV-LFBNJJMOSA-N |
| Short Description: | C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TNF-alpha, and transcription factors c-Jun and NF-kappaB in histone-stimulated murine skin tissue. For mulations containing cer(t18:0/18:0) have been used used in cosmetics as a skin protectants as they reduce water loss to prevent epidermal dehydration and irritation. |
| Stock amount: | 5 |