5(S)-HETE lactone

Chemical Structure Depiction of
5(S)-HETE lactone
Pack Size, mg
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Compound characteristics

Compound ID: CE04-1808
Compound Name: 5(S)-HETE lactone
Molecular Weight: 302.46
Molecular Formula: C20 H30 O2
CAS Number: 127708-42-3
Smiles: CCCCC\C=C/C\C=C/C\C=C/C=C/[C@@H]1CCCC(=O)O1
InChI Key: QZMAEYDIHWEEAF-MSFIICATSA-N
Short Description: 5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (+-)5-HETE lactone to inhibit rat basophilic leu kemia cell 5-lipoxygenase (IC50 = 27 muM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.
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