15(S)-Latanoprost
Chemical Structure Depiction of
15(S)-Latanoprost
15(S)-Latanoprost
Compound characteristics
| Compound ID: | CE04-2053 |
| Compound Name: | 15(S)-Latanoprost |
| Molecular Weight: | 432.6 |
| Molecular Formula: | C26 H40 O5 |
| CAS Number: | 145773-22-4 |
| Smiles: | CC(C)OC(CCC\C=C/C[C@H]1[C@H](C[C@H]([C@@H]1CC[C@@H](CCc1ccccc1)O)O)O)=O |
| InChI Key: | GGXICVAJURFBLW-LFCBLZOASA-N |
| Short Description: | 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 mug dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product. |
| Stock amount: | 50 |