Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Chemical Structure Depiction of
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Compound characteristics
| Compound ID: | CE04-5516 |
| Compound Name: | Dapagliflozin ((2S)-1,2-propanediol, hydrate) |
| Molecular Weight: | 502.99 |
| Molecular Formula: | C21 H25 Cl O6.C3 H8 O2.H2 O |
| CAS Number: | 960404-48-2 |
| Smiles: | CCOc1ccc(Cc2cc(ccc2[Cl])[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)cc1.C[C@@H](CO)O.O |
| InChI Key: | GOADIQFWSVMMRJ-VOSRMZSRSA-N |
| Short Description: | Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in dev elopment for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. |
| Pathway: | GPCR/G Protein |
| Target: | SGLT |
| Type of molecule: | FDA Approved |
| Alias: | Dapagliflozin propanediol monohydrate , BMS-512148 (2S)-1,2-propanediol, hydrate |
| Stock amount: | 7230 |