Pyrrole-2-carboxylic acid
Chemical Structure Depiction of
Pyrrole-2-carboxylic acid
Pyrrole-2-carboxylic acid
Compound characteristics
| Compound ID: | CE04-5757 |
| Compound Name: | Pyrrole-2-carboxylic acid |
| Molecular Weight: | 111.1 |
| Molecular Formula: | C5 H5 N O2 |
| CAS Number: | 634-97-9 |
| Smiles: | c1cc(C(O)=O)[nH]c1 |
| InChI Key: | WRHZVMBBRYBTKZ-UHFFFAOYSA-N |
| Short Description: | Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxid ase. The latter relationship results from the lability of the direct oxidation product, A'-pyrroline-4-hydroxy-2-carboxylic acid, which loses water spontaneously to form the pyrrole. A similar reactio n is catalyzed by the more specific allohydroxy-D-proline oxidase of Pseudomonas. In whole animal observations, pyrrole-2-carboxylate (PCA) ' was identified in rat or human urine after administration of the D-isomers of hydroxyproline, a finding ascribable to the action of D-amino acid oxidase. Urinary excretion of N-(pyrrole-2-carboxyl) glycine has been reported in a 5-year-old affected with type II hyperprolinemia; The child has mild developmental delay, recurrent seizures of the grand mal type and EEG alterations. |
| Pathway: | Metabolism |
| Target: | Endogenous Metabolite |
| Alias: | 2-Pyrrolecarboxylic acid , Minaline |
| Stock amount: | 3588 |