Pamiparib
Chemical Structure Depiction of
Pamiparib
Pamiparib
Compound characteristics
| Compound ID: | CE04-6269 |
| Compound Name: | Pamiparib |
| Molecular Weight: | 298.32 |
| Molecular Formula: | C16 H15 F N4 O |
| CAS Number: | 1446261-44-4 |
| Smiles: | C[C@@]12CCCN2CC2c3c4c(cc(cc4[nH]c13)F)C(NN=2)=O |
| InChI Key: | DENYZIUJOTUUNY-MRXNPFEDSA-N |
| Short Description: | Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers including the solid tumor |
| Pathway: | Chromatin/Epigenetic|||DNA Damage/DNA Repair |
| Target: | PARP |
| Type of molecule: | Approved/Clinical |
| Alias: | BGB-290 |
| Stock amount: | 324 |