Darapladib
Chemical Structure Depiction of
Darapladib
Darapladib
Compound characteristics
| Compound ID: | CE04-8122 |
| Compound Name: | Darapladib |
| Molecular Weight: | 666.78 |
| Molecular Formula: | C36 H38 F4 N4 O2 S |
| CAS Number: | 356057-34-6 |
| Smiles: | CCN(CC)CCN(Cc1ccc(cc1)c1ccc(cc1)C(F)(F)F)C(CN1C2CCCC=2C(N=C1SCc1ccc(cc1)F)=O)=O |
| InChI Key: | WDPFJWLDPVQCAJ-UHFFFAOYSA-N |
| Short Description: | Darapladib (SB-480848)(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2). |
| Pathway: | Metabolism |
| Target: | Phospholipase |
| Type of molecule: | Clinical |
| Alias: | SB-480848 |
| Stock amount: | 21378 |