Canertinib
Chemical Structure Depiction of
Canertinib
Canertinib
Compound characteristics
| Compound ID: | CE04-8353 |
| Compound Name: | Canertinib |
| Molecular Weight: | 485.94 |
| Molecular Formula: | C24 H25 Cl F N5 O3 |
| CAS Number: | 267243-28-7 |
| Smiles: | C=CC(Nc1cc2c(Nc3ccc(c(c3)[Cl])F)ncnc2cc1OCCCN1CCOCC1)=O |
| InChI Key: | OMZCMEYTWSXEPZ-UHFFFAOYSA-N |
| Short Description: | Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, p roliferation and hypoxia as determined by PET. |
| Pathway: | Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling |
| Target: | EGFR |
| Type of molecule: | Clinical |
| Alias: | CI-1033 , PD-183805 |
| Stock amount: | 329 |